Special Lecture 1
Day 1, January 23 (Tue.) 13:35 - 14:25
8F Main Hall
Chair: Kumiko Ogawa (National Institute of Health Sciences)
SL-1
Investigation of the resistance to aging and carcinogenesis in the naked mole-rat, the longest-lived rodent
○Kyoko Miura
Department of Aging and Longevity Research, Faculty of Life Sciences, Kumamoto University
Special Lecture 2
Day 2, January 24 (Wed.) 11:10 - 12:00
8F Main Hall
Chair: Katsuhiko Yoshizawa (Mukogawa Women's University)
SL-2
The actual process of assessment of the effect of food on health at the Food Safety Commission
○Satoshi Asano
Food Safety Commission of Japan, Cabinet Office, Government of Japan
Symposium 1
Interpretation of Histopathological Changes Deepened by New Technologies and Insights
Day 1, January 23 (Tue.) 10:25 - 12:25
8F Main Hall
Chair: Masami Suzuki (Central Institute for Experimental Animals)
Min Gi (Osaka Metropolitan University Graduate School of Medicine)
S1-1
Histopathological image analysis by Spatial Transcriptome
○Shumpei Ishikawa1,2)
1)Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo,
2)Division of Pathology, EPOC, National Cancer Center
S1-2
Deciphering metabolic systems of cancer and stroma by imaging metabolomics
○Makoto Suematsu1,2)
1)Central Institute for Experimental Medicine and Life Science,
2)Keio University WPI-Bio2Q Research Center
S1-3
Linear ubiquitination-mediated regulation of inflammatory and immune responses and its involvement in diseases
○Fuminori Tokunaga
Department of Medical Biochemistry, Graduate School of Medicine, Osaka Metropolitan University
S1-4
Immortalization of primary human cells and its application to cancer research
○Tohru Kiyono
Project for Prevention of HPV-related Cancer, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center
Symposium 2
Current and Future Perspectives of AI Technology in Toxicologic Pathology
Day 2, January 24 (Wed.) 9:00 - 11:00
8F Main Hall
Chair: Hisashi Anayama (Takeda Pharmaceutical Co., Ltd.)
Kochi Kakimoto (BoZo Research Center Inc.)
S2-1
Activities on medical Bigdata research center in National Institute of Informatics
○Masaru Kitsuregawa1,2)
1)Inter-University Research Institute Corporation, Research Organization of Information and Systems,
2)The University of Tokyo
S2-2
Introducing Minitox 1.0: A new decision support AI tool for the bench toxicologic pathologist
○Daniel G. Rudmann
Charles River Laboratories
S2-3
Digital pathology and artificial intelligence toward clinical practice
○Tetsuya Tsukamoto1), Yuka Kiriyama1,2), Ayano Michiba1)
1)Department of Diagnostic Pathology, Fujita Health University,
2)Department of Diagnostic Pathology, Narita Memorial Hospital
S2-4
JPMA's initiative for AI pathology
○Izumi Matsumoto1,2)
1)Sumitomo Pharma Co., Ltd.,
2)AI Pathology Task Force, Non-clinical Evaluation Expert Committee, Drug Evaluation Committee, Japan Pharmaceuticals Manufacturers Association
Panel Discussion
Do we know everything already? - The ever troublesome world of "boundaries of proliferative lesions"
Day 2, January 24 (Wed.) 13:10 - 14:40
8F Main Hall
Chair: Atsuhiko Kato (Chugai Pharmaceutical Co., Ltd.)
Junko Sato (Mediford Corporation)
PD-1
The border between benign and malignant hepatocellular proliferative lesions
PD-2
The border between skin tumors
PD-3
The border between thyroid follicular proliferative lesions
PD-4
The border between benign and malignant lung tumors
Panelists:
Toshihisa Fujiwara (Shin Nippon Biomedical Laboratories, Ltd.)
Hijiri Iwata (LunaPath Co.Ltd., Laboratory of Toxicologic Pathology)
Takeshi Izawa (Osaka Metropolitan University)
Katsuhiro Miyajima (Tokyo University of Agriculture)
Toko Ohira (Shanghai InnoStar Bio-tech Co., Ltd.)
Etsuko Ohta (Global Drug Safety, Eisai Co., Ltd.)
Yoshimasa Okazaki (AnaPath Services GmbH)
Kiyokazu Ozaki (Setsunan University)
Yuko Yamaguchi (Bozo Research Center Inc.)
IATP Maronpot Guest Lecture
Day 1, January 23 (Tue.) 15:45 - 16:35
8F Main Hall
Chair: Shim-mo Hayashi (National Institute of Health Sciences)
IATP
Cell proliferation and carcinogenesis
○Samuel M. Cohen
University of Nebraska Medical Center
Workshop 1
Day 1, January 23 (Tue.) 9:15 - 10:15
8F Main Hall
Chair: Katsuhiro Miyajima (Tokyo University of Agriculture)
Hiroko Kokoshima (Shin Nippon Biomedical Laboratories, Ltd.)
W1-1
Evaluating hepatic metabolism and carcinogenicity of dimethylarsinic acid using humanized liver mice model
○Arpamas Vachiraarunwong1), Min Gi1,2), Masaki Fujioka2), Shugo Su2), Guiyu Qiu2), Runjie Guo1), Anna Kakehashi2), Hideki Wanibuchi2)
1)Department of Environmental Risk Assessment, Osaka Metropolitan University Graduated School of Medicine,
2)Department of Molecular Pathology, Osaka Metropolitan University Graduate School of Medicine
W1-2
Angiotensin II receptor blocker suppresses liver injury and fibrosis in rat non-alcoholic steatohepatitis model
○Xiaochen Kuang, Aya Naiki-Ito, Masayuki Komura, Hiroyuki Kato, Satoru Takahashi
Dept. Exp. Pathol. Tumor Biol., Nagoya City Univ.
W1-3
Analysis of the relationship between blood levels of Mac-2 binding protein and progression of liver fibrosis in mice
○Ryohei Kamino1), Teppei Uechi1), Marika Tohma1), Noriko Kemuriyama2), Tomohiko Sasase3), Tatsuya Maekawa2), Dai Nakae2,4), Katsuhiro Miyajima1,2)
1)Department of Food and Nutritional Science, Graduate School of Agriculture, Tokyo University of Agriculture,
2)Department of Nutritional Science and Food Safety, Faculty of Applied Biosciences, Tokyo University of Agriculture,
3)Laboratory of Animal Physiology and Functional Anatomy, Graduate School of Agriculture, Kyoto University,
4)Department of Medical Sports, Faculty of Health Care and Medical Sports, Teikyo Heisei University
W1-4
Involvement of epigenetic mechanism by altered DNA methylation in early process of renal carcinogenesis by ochratoxin A
○Shunsuke Ozawa1,2), Ryota Ojiro1,2), Qian Tang1,2), Xinyu Zou1,2), Toshinori Yoshida1,2), Makoto Shibutani1,2)
1)Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology,
2)Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology
Workshop 2
Day 1, January 23 (Tue.) 14:35 - 15:35
8F Main Hall
Chair: Toshihisa Fujiwara (Shin Nippon Biomedical Laboratories, Ltd.)
Aya Naiki-Ito (Nagoya City University Graduate School of Medical Sciences)
W2-1
Elucidation of 3D structure of cutaneous nerve fibers and establishment a 3D quantitative analysis method
○Minori Inanaga, Erina Kaitani, Ayumi Matsuda, Tetsuro Matsuura, Kiyokazu Ozaki
Laboratory of Pathology, Faculty of Pharmaceutical Sciences, Setsunan University
W2-2
Development of deep learning-based image analysis models and its application in rat early-stage toxicity studies
○Taishi Shimazaki1), Yuzo Yasui1), Kyotaka Muta1), Naohito Yamada1), Thomas Tijo2), Joshi Uttara2), Toshiyuki Shoda1)
1)Toxicology Research Laboratories, Yokohama Research Center, Central Pharmaceutical Research Institute, Japan Tobacco Inc.,
2)AIRA Matrix Private Limited
W2-3
Investigating methods for quantifying lipid content in a NAFL model using HALO® and HALO AI™ image analysis
○Ayano Hirako1), Saori Matsuo1), Masaki Yamazaki1), Yu Oikawa2), Eri Joyashiki2), Atsuhiko Kato1)
1)Safety and Bioscience Research Dept., Chugai Pharmaceutical Co., Ltd.,
2)Discovery Pharmacology 2 Dept., Chugai Pharmaceutical Co., Ltd.
W2-4
Liver lesions detection with histological representation learned by tissue images of control rats
○Mitsuru Negishi1), Shunsuke Tominaga1), Akira Inomata2)
1)Imaging Technology Center, FUJIFILM Corporation,
2)Bio Science & Engineering Laboratories, FUJIFILM Corporation