The 41st Annual Meeting of the Japanese Society of Toxicologic Pathology The 41st Annual Meeting of the Japanese Society of Toxicologic Pathology

Program

Program (PDF)

Luncheon Seminar and Evening Seminar Information

Luncheon Seminar and Evening Seminar Program (PDF)
EV1 AIRA Matrix / Japan SLC (PDF)
(In Japanese)
L1 LunaPath Institute of Toxicologic Pathology (PDF)
(In Japanese)
L2 AnaPath Services GmbH (PDF)
(In Japanese)
L3 Labcorp Laboratories Japan G.K (PDF)
(In Japanese)
L4 Shin Nippon Biomedical Laboratories (PDF)
(In Japanese)

Program (2024.12)

Special Lecture 1
Day1 January 30th (Thu) 15:50 - 16:50
Lecture Hall (1F Main Hall)

Chair: Aya Naiki-Ito (Nagoya City University)
Kochi Kakimoto (BoZo Research Center Inc.)

SL-1
Immunoregulation by designer exosomes and its quality control
○Rikinari Hanayama1,2)
  • 1)WPI Nano Life Science Institute, Kanazawa University,
  • 2)Department of Immunology, Graduate School of Medical Sciences, Kanazawa University
Special Lecture 2
Day2 January 31st (Fri) 13:35 - 14:35
Lecture Hall (1F Main Hall)

Chair: Satoshi Furukawa (Nissan Chemical Corporation)
Toshihisa Fujiwara (Shin Nippon Biomedical Laboratories Ltd.)

SL-2
Nanotechnology for future medicine
○Kazunori Kataoka
Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion
Symposium
Considering the future of toxicological pathology from the current status of animal experiments.
Day2 January 31st (Fri) 08:50 - 10:25
Lecture Hall (1F Main Hall)

Chair: Shugo Suzuki (Osaka Metropolitan University)
Takeshi Izawa (Osaka Metropolitan University)

S-1
Current status of animal experiments
○Ryo Takai
Chugai Pharmaceutical Co., Ltd.
S-2
Animal experiments from the perspective of regulatory authorities
○Jihei Nishimura
Pharmaceuticals and Medical Devices Agency
S-3
Interface between toxicologic pathology and in vitro, and its future
○Tadahiro Shinozawa
Takeda Pharmaceutical Company Limited
Interactive Symposium
How Should Toxicologic Pathologists Recognize AI Automated Diagnostic Models?
Day1 January 30th (Thu) 13:20 - 15:40
Lecture Hall (1F Main Hall)

Chair: Masako Imaoka (Daiichi Sankyo Co., Ltd.)
Saori Matsuo (Chugai Pharmaceutical Co., Ltd.)

IS
How should toxicologic pathologists recognize AI automated diagnostic models?
○Masako Imaoka1), Saori Matsuo2)
  • 1)Daiichi Sankyo Co., Ltd.,
  • 2)Chugai Pharmaceutical Co., Ltd.
IS-1
The application and limitations of AI pathology models
○Makoto Shirai, Masako Imaoka, Yoshimi Tsuchiya
Daiichi Sankyo Co., Ltd.
IS-2
Progress of digitalization in nonclinical pathology in Europe
○Yumi Kangawa1), Brian Knight2), Robin Stierkat3), Sarah Kirschner-Kitz3), Gabriele Pohlmeyer-Esch3)
  • 1)Nippon Boehringer Ingelheim, Japan,
  • 2)Boehringer Ingelheim, USA,
  • 3)Boehringer Ingelheim, Germany
IS-3
The guideline for pathology AI by JSP, summary and issues
○Taizo Shiraishi
Kuwana Medical Center
Discussion
Panelists:
Makoto Shirai (Daiichi Sankyo Co., Ltd.), Yumi Kangawa (Nippon Boehringer Ingelheim), Taizo Shiraishi (Kuwana Medical Center), Akira Inomata (FUJIFILM Corporation), Etsuko Ohta (Eisai Co., Ltd.), Tsubasa Saito (BoZo Research Center Inc.), Jihei Nishimura (Pharmaceuticals and Medical Devices Agency)
Panel Discussion
Commencing the investigation of toxicity mechanisms from pathological findings
Day2 January 31st (Fri) 10:35 - 12:15
Lecture Hall (1F Main Hall)

Chair: Yuki Kato (Shionogi & Co., Ltd.)
Tomoya Sano (Takeda Pharmaceutical Company Limited)

PD
Commencing the investigation of toxicity mechanisms from pathological findings
○Tomoya Sano1), Yuki Kato2)
  • 1)Takeda Pharmaceutical Company Limited,
  • 2)Shionogi & Co., Ltd.
PD-1
Histopathological changes in the immune system induced by an immunomodulatory drug and their mechanism of action
○Tetsuya Sakairi
Mitsubishi Tanabe Pharma Corporation
PD-2
Investigation of the mode of action and human relevance of adverse findings in the urinary bladder
○Kenji Koyama
Shionogi & Co., Ltd.
PD-3
Species differences of the corneal toxicity induced by a certain pesticide in rats
○Yusuke Kuroda
Nissan Chemical Corporation
PD-4
Mechanistic investigation of oligonucleotide-induced toxicity
○Yuichi Takai
Takeda Pharmaceutical Company Limited
IATP Maronpot Guest Lecture
Day1 January 30th (Thu) 17:00 - 18:00
Lecture Hall (1F Main Hall)

Chair: Kouji Tanake (BoZo Research Center Inc.)
Katsuhiko Yoshizawa (Mukogawa Womenʼs University)

IATP
Thymus findings induced by a RORγt antagonist
○Thomas Nolte
Boehringer Ingelheim, Germany
Workshop
Day1 January 30th (Thu) 09:20 - 11:00
Lecture Hall (1F Main Hall)

Chair: Mami Kouchi (Sumitomo Pharma Co., Ltd.)
Akihiko Sugiyama (Okayama University of Science)

W-1*
Mechanism of chromothripsis via acetamide-induced large micronuclei
○Yohei Yamagami1,2), Yuji Ishii1), Shinji Takasu1), Meili Soma1), Kengo Kasamatsu1,3),Takeshi Toyoda1), Tomoaki Murakami2), Kumiko Ogawa1)
  • 1)Division of Pathology, National Institute of Health Sciences,
  • 2)Laboratory of Veterinary Toxicology, Tokyo University of Agriculture and Technology,
  • 3)Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
W-2*
A novel support vector machine-based one-day, single-dose prediction model of genotoxic hepatocarcinogenicity in rats
○Guiyu Qiu1), Min Gi1), Shugo Suzuki2), Masaki Fujioka2), Anna Kakehashi2), Arpamas Vachiraarunwong1), Ikue Noura2), Runjie Guo1), Hideki Wanibuchi1)
  • 1)Department of Environmental Risk Assessment, Osaka Metropolitan University Graduate School of Medicine,
  • 2)Department of Molecular Pathology, Osaka Metropolitan University Graduate School of Medicine
W-3*
ALDH2 gene polymorphism can progress western diet-induced MASLD to steatohepatitis
○Sakura Fujiwara, Jun Nakamura, Yuki Takami, Mitsuru Kuwamura, Takeshi Izawa
Laboratory of Veterinary Pathology, Osaka Metropolitan University
W-4*
Investigation of actinin-4 expression through proteome analysis in a mouse model of pancreatitis
○Hiroyuki Kato, Aya Naiki-Ito, Masayuki Komura, Satoru Takahashi
Dep. Exp. Pathol. Tumor Biol., Nagoya City Univ., Grad Sch Med Sci
W-5*
Phenotype analysis of a genome-edited mouse with a germline variant in the 5' region of the Apc gene (ApcΔ155/+ mice)
○Teruaki Hirota1,2), Hiroki Sakai1,2,3), Akihiro Hirata1,2,3)
  • 1)Joint Graduate School of Veterinary Sciences, Gifu University,
  • 2)Laboratory of Veterinary Pathology, Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University,
  • 3)Center for One Medicine Innovative Translational Research (COMIT), Gifu University
W-6*
Carbon nano-horns (CNH) and carbon nano-brushes (CNB) do not induce lung cancer or pleural mesothelioma in the rat lung
○Omnia Hosny1,2,3), Dina Saleh4), David Alexander1), William Alexander1), Hiroshi Takase5), Akihiko Hirose6), Jun Kanno7), Aya Naiki-Ito2), Satoru Takahashi2), Masako Yudasaka8), Ryota Yuge9), Hiroyuki Tsuda1)
  • 1)Nanotoxicology Lab Project, Nagoya City University,
  • 2)Department of Experimental Pathology and Tumor Biology, Nagoya City University,
  • 3)Department of Forensic Medicine and Clinical Toxicology, Aswan University,
  • 4)Department of Forensic Medicine and Clinical Toxicology, Assuit University,
  • 5)Core Laboratory, Nagoya City University,
  • 6)Chemicals Evaluation and Research Institute (CERI),
  • 7)National Institute Hygienic Sciences (NIHS),
  • 8)Meijo University,
  • 9)Secure System Platform Research Laboratories, NEC Corporation